21.
Costs were examined from a healthcare and societal perspective and were derived using the consumer price index for healthcare.7. Saint S, 36 . Because of increasing antimicrobial resistance, it is important not to treat patients with asymptomatic bacteriuria unless there is evidence of potential benefit. Turrentine MA, Colicchia LC, Hirsch E, et al. Oden A,
The take home message is that treatment of ASBU is common and results in significant patient harm. GBS can cause bladder and uterine infections for the mother. Galinski J,
coli, whereas a nursing home resident with a catheter is more likely to have multi-drug–resistant polymicrobic flora(e.g.,P. et al. with persistent bacteriuria after two or more treatment courses (see Table 3) If group B Streptococcus (GBS) is isolated in urine prophylactic antibiotics must be offered during labour, as GBS bacteriuria indicates high colonisation levels Acute cystitis in pregnant women1, 3-5 Krupa-Wojciechowska B. 1984;132:943–6.
Heavy urinary colonization with GBS in pregnancy contributes to maternal pyelonephritis and preterm birth; therefore, treatment of asymptomatic bacteriuria with GBS colony count ≥ 100 000 CFU/mL is an accepted and recommended strategy for the prevention of adverse maternal and perinatal outcomes. 1989;129:372–9. Asymptomatic bacteriuria is common, with varying prevalence by age, sex, sexual activity, and the presence of genitourinary abnormalities(Table 13–8). Bradley S, 35.
Scholes D, The clinical course of untreated asymptomatic bacteriuria in diabetic patients–14-year follow-up.
Galinski J, •GBS colonisation in current pregnancy •GBS bacteriuria in current pregnancy • Preterm labour (< 37+0 weeks) • Previous baby with EOGBSD • ROM > 18 hours o If labour established: at 14 hours after ROM and birth is unlikely by 18 hours, then commence IAP • Temperature ≥ 38 oC 32 The preferred antibiotic should be selected based on drug safety considerations and local resistance patterns.
Start with … Found inside – Page 294Duration of treatment Current standard treatment for ASB in pregnant women involves 3- or 7-day antibiotic regimens. ... of re- spondents (65/85 respondents) treat low colony counts of asymptomatic GBS bacteriuria during pregnancy.19 J. Infection 1992; 20 Suppl 4:S313. Digranes A. Routine screening for asymptomatic bacteriuria is recommended in pregnant women, and laboratories should screen urine culture specimens for the presence of GBS in concentrations of 104 colony-forming units (cfu)/ml or greater.
Infectious Diseases Society of America and the Food and Drug Administration.
Perinatal Services BC Group B Streptococcus in the Perinatal Period 2 • If a woman with pre-labour rupture of membranes at 37 or greater weeks’ gestation is positive for group B streptococcus by vaginal/rectal swab culture screening, has had group B streptococcus bacteriuria in the current pregnancy, or has had
Maternal Group B Streptococcus in p endorsed by RANZCOG 2003 Review due July 2022 .
et al. Treatment of any bacteriuria with colony counts ≥100 000 CFU/mL in pregnancy is an accepted and recommended strategy and includes treatment with appropriate antibiotics (II-2A). Treatment of asymptomatic Can I Give Birth Safely if I have Coronavirus?
Found inside – Page 237One to 2 weeks after completion of treatment, a further MSU should be collected to confirm eradication of the infection. ... Asymptomatic bacteriuria, GBS, Listeria monocytogenes and VZV are of significance in pregnancy and in the ... Chenoweth CE.
GBS affects about 1 in every 2,000 babies in the United States. 2002;347:1576–83. Mattarelli G, Previous infant with invasive GBS disease. Clinically inapparent (asymptomatic) bacteriuria in ambulatory elderly men: epidemiological, clinical, and microbiological findings.
This content is owned by the AAFP. Clinical Management of Complicated Urinary Tract Infection et al.
Infectious Diseases Society of America; American Society of Nephrology; American Geriatric Society.
et al. Gupta K, While acting as a stand-alone text on obstetric care, this volume also forms part of a three-volume set - all authored by leading authorities - on the entirety of obstetric and gynecologic practice.
According to the CDC, if you have tested positive and are not high risk, your chances of delivering a baby with GBS are: If you test positive for GBS and meet the high-risk criteria, your physician will probably recommend giving you antibiotics through an IV during your delivery to prevent your baby from becoming ill. Screening for asymptomatic bacteriuria in pregnancy.
For Group B Strep: • Penicillin VK 500 mg PO QID x 5-7 days • Amoxicillin 500 mg PO TID x 5-7 days For pyelonephritis: IV therapy required until afebrile x 48 hrs, then switch to PO antibiotics if appropriate • Ceftriaxone 2g IV q 24hrs • Gentamicin (dosing per pharmacy) • Duration of treatment: 10-14 days total Table 3. Warren JW, Wilson JM, Jungner YG.
Scand J Infect Dis. How long should catheter-acquired urinary tract infection in women be treated? Lancet.
Dahlen-Nilsson I, Mattarelli G, Patients with chronic indwelling Foley catheters are uniformly bacteriuric, but treatment is warranted only if the patient is symptomatic. Low risk of bacteremia during catheter replacement in patients with long-term urinary catheters. One-way sensitivity analysis results remained robust and showed mean ICER for costs and probabilities that were lower than a willingness to pay threshold of $100,000/QALYs gained.
For men, a single specimen with one bacterial species isolated in a quantitative count of at least 100,000 CFUs per mL. 13. Urinary Tract Infection and Asymptomatic Bacteriuria Guidance Fingold S, Earlier onset GBS cases were prevented with strategies A and B compared to no GBS screening.
Consequences of asymptomatic bacteriuria in women with diabetes mellitus. As such, physicians include testing as a routine part of prenatal care. Getting a UTI during pregnancy is pretty common, especially after week six of pregnancy. That’s because as baby grows, it puts plenty of pressure on your bladder and can prevent it from draining normally. Any bacteria that gets trapped in there can cause an infection.
Kaye D. The recommended choice of antibiotic treatment of GBS bacteriuria is penicillin . Bullen M. Infectious Diseases Society of America guidelines for the diagnosis and treatment of asymptomatic bacteriuria in adults. Levison ME, Am J Kidney Dis. Objective: The objective of the study was to determine the frequency of adverse pregnancy outcomes in women with untreated asymptomatic group B beta-hemolytic streptococcal (GBS) bacteriuria during pregnancy.
Efficiency of screening for the recurrence of antenatal group B streptococcus colonization in a subsequent pregnancy: A systematic review and meta-analysis with independent patient data. et al.
Fanaroff and Martin's Neonatal-Perinatal Medicine E-Book: ... Bacteriuria in a population sample of women: 24-year follow-up study.
Rubin RH, Obstet Gynecol. Epidemiology and risk factors for urinary tract infection following spinal cord injury. Schneeberger PM,
The American Academy of Pediatrics (AAP), jointly with the American College of
Roganti A.
indication pregnant women colonized with GBS at 35-37 weeks; prior birth of an infant with GBS disease; unknown status of antepartum culture 32. Probst W,
Hebel JR,
Canupp KC, Krupa-Wojciechowska B.
Plante DA. Mossey J, Pregnant women should undergo vaginal-rectal screening for GBS colonization at 36w0d – 37w6d (screening valid up to at least 41w0d) Intrapartum antibiotic prophylaxis is recommended for women.
Nicolle LE. Found inside – Page 72If other factors are considered , however , routine culturing for GBS in pregnant women and treatment of those harboring the ... Bacteriuria in Pregnancy E.G. Wood and H.C. Dillon Jr. AM JOBSTET GYNECOL 1981 Jul 1 ; 140 ( 5 ) : 515-20 .
Evaluation of new anti-infective drugs for the treatment of urinary tract infection.
Antimicrobial treatment in diabetic women with asymptomatic bacteriuria.
Group B streptococcal infection Vaginal colonisation with group B streptococci is strongly associated with preterm rupture of membranes,labour and delivery and is a proven cause of neonatal sepsis.Evidence relating group B streptococcal bacteriuria with similar consequences is less well established. Waites KB, Boscia JA,
Norman DC,
J Am Geriatr Soc. Infectious Diseases Society of America and the Food and Drug Administration. Treating asymptomatic bacteriuria in patients with diabetes, older persons, patients with or without indwelling catheters, or patients with spinal cord injuries has not been found to improve outcomes. Yoshikawa TT.
Schneeberger PM,
Rates of bacteriuria in various bladder-emptying methods. 1999;29:745–58.... 2. For women who are group B strep carriers, antibiotics given before labor begins are not effective at preventing the transmission of the group B bacteria.
Mayhew WJ,
Shapiro ED, Chaudhry A,
Intravenous antibiotics are used to treat mothers and newborns with early-onset GBS.
A woman may test positive at certain times and negative at others.
Found inside – Page 312Any woman with ruptured membranes at term with GBS should be advised regarding expediting delivery. ... (UTI). Urinary tract infections (UTIs) are commonly encountered in pregnancy. Treatment for asymptomatic bacteriuria is advised, ...
However, in the asymptomatic patient, cloudy or foul smelling urine is not an indication for urinalysis, culture, or antimicrobial treatment.
According to 2019 guidelines, GBS ASB at a threshold of at least 10 5 CFU/mL during pregnancy should; not be treated with antibiotics.
Found inside – Page 283IAP for the prevention of GBS EOS can be administered to pregnant women during labor based on ( 1 ) specific risk factors for ... Pregnant women with documented GBS bacteriuria during pregnancy or who previously delivered an infant who ...
74/No. Uman G,
Kobasa WD, JAMA. Please click here to continue without javascript..
Horoszek-Maziarz S,
Found inside – Page 357Intrapartum transmission may lead to neonatal GBS infection: a. Women with documented GBS bacteriuria in the current pregnancy should be treated at the time of labour or rupture of membranes with appropriate intravenous (IV) antibiotics ... GBS bacteriuria during current pregnancy 3. Most cases occur…, Gestational diabetes is diabetes diagnosed for the first time during pregnancy. If it is, the UTI should be treated with antibiotics before it progresses to a life-threatening infection. Kass EH. In women or men, a single specimen with one bacterial species isolated in a quantitative count of at least 100 CFUs per mL. GBS remains susceptible to the beta-lactams, but individuals with a penicillin allergy should have antibiotic sensitivities determined. 2005;40:643–54. 1990;38:1209–14.
Management of group B streptococcal bacteriuria in … Bullen M. Testing for and treating GBS in pregnancy. About 1 in 4 pregnant women carry GBS in their rectum or vagina.
Indicated for bacteriuria that persists after 2 or more courses of therapy: o Macrobid 50 to 100 mg PO qhs, for duration of pregnancy. Screen pregnant persons for asymptomatic bacteriuria using a midstream, clean-catch urine culture at the first prenatal visit or at 12 to 16 weeks of gestation, whichever is earlier.
Harding GK, Women with GBS bacteriuria identified during the current pregnancy should be offered IV antimicrobial prophylaxis during delivery .
Duration of treatment for asymptomatic bacteriuria during pregnancy.
Llewellyn-Jones Fundamentals of Obstetrics and Gynaecology ...
Dahlen-Nilsson I, This is rare and happens to 1 or 2 babies out of 100 when the mother does not receive treatment with antibiotics during labor. Address correspondence to Richard Colgan, M.D., Dept. Heise RH, Bengtsson C, Cowgill K, Taylor TH Jr, Schuchat A, Schrag S. Report from the CDC. 2003;17:411–32. It is best to discuss the pros and cons of taking antibiotics with your health care provider. 1993;74:691–5. Bengtsson C, J Urol. This is the third edition of this guideline. Meta-analysis of the relationship between asymptomatic bacteriuria and preterm delivery/low birth weight. Found insidePatients with diabetes gravidarum are also more likely to suffer from GBS asymptomatic bacteriuria. Growth greater than 105 CFU/ml requires treatment in pregnancy and intrapartum antibiotics according to the RCOG guidelines ... Muncie HL,
Roganti A.
There is a 2-10%
Positive GBS urinary tract infection at any time during the pregnancy is a marker of heavy colonization, and these patients should receive prophylaxis even if GBS culture is negative between 35 to 37 weeks[2].
Who delivered a previous infant with GBS disease. Williams and colleagues demonstrated that universal screening for GBS at 36 0/7 to 37 6/7 weeks of gestation is cost-effective.7 In addition, screening for GBS meets the Wilson and Jungner’s criteria, which includes that GBS remains an important health problem; GBS infection has a well-described latent stage and natural history; there are suitable testing algorithms for GBS diagnosis and treatment; case finding for GBS involves a continuous process; and the total cost of finding a case of GBS during pregnancy is economically plausible when compared to the alternative of no screening, resulting in early-onset neonatal GBS infection.11, The ACOG practice bulletin recommends intrapartum antibiotic prophylaxis for pregnant women who screen positive for GBS in a current pregnancy.8 Antibiotic prophylaxis also is recommended for pregnant women who are GBS unknown presenting in labor with risk factors for GBS (GBS bacteriuria earlier in pregnancy, preterm labor, history of a previous neonate with early-onset GBS, maternal pyrexia [> 38°C], and prolonged rupture of membranes [> 18 hours]). The clinical course of untreated asymptomatic bacteriuria in diabetic patients–14-year follow-up. Hoopes JM, A person viewing it online may make one printout of the material and may use that printout only for his or her personal, non-commercial reference. Mean incremental cost-effectiveness ratios (ICERs) were used to express cost-effectiveness under a willingness to pay threshold of $100,000/QALY gained. 11.
It is not clear whether antibiotic treatment for this condition is of benefit for non-pregnant adults. Women found to have vaginal or rectal colonisation with GBS during pregnancy should not have antenatal treatment Treatment of asymptomatic GBS or other bacteriuria in pregnancy reduces the risk of maternal pyelonephritis.
Smaill F.
Oden A, Kincaid-Smith P, Low DE, Wadland WC, Evaluation of new anti-infective drugs for the treatment of urinary tract infection. Costs were expressed in 2019 U.S. dollars, and health utilities were expressed in QALYs and discounted at 3% per year.
Urinary infection and complications during clean intermittent catheterization following spinal cord injury.
2006 Sep 15;74(6):985-990. Urinary tract infections (UTIs) are one of the most common infections for which antibiotics are prescribed.
Group B Streptococcus also known as Group B Strep Infection (GBS) is a type of bacterial infection that can be found in a pregnant woman’s vagina or rectum. 15. / Vol. Clinicians should be aware of this when making decisions about the treatment of possible UTI. Found inside – Page 399Early diagnosis and aggressive treatment of infection during pregnancy may substantially reduce the associated morbidity ... This increased risk can be diminished by antibiotic treatment.119 The presence of GBS bacteriuria is a special ...
Does asymptomatic bacteriuria predict mortality and does antimicrobial treatment reduce mortality in elderly ambulatory women [Published correction appears in Ann Intern Med 1994;121:901]?.
Regardless of planned mode of birth, all pregnant women should undergo antepartum screening for GBS at 36 0/7–37 6/7 weeks of gestation, unless intrapartum antibiotic prophylaxis for GBS is indicated because of GBS bacteriuria during the pregnancy or because of a history of a previous GBS-infected newborn.
Rates of bacteriuria in various bladder-emptying methods. Bacteriuria during follow-up in patients with spinal cord injury: I. Stapleton AE,
GBS bacteriuria should be treated, whether symptomatic or not (24). Although women with asymptomatic bacteriuria are more likely to have subsequent symptomatic UTIs, treatment of asymptomatic bacteriuria does not decrease the frequency of symptomatic UTI or prevent further episodes of bacteriuria. •GBS colonisation in current pregnancy •GBS bacteriuria in current pregnancy • Preterm labour (< 37+0 weeks) • Previous baby with EOGBSD • ROM > 18 hours o If labour established: at 14 hours after ROM and birth is unlikely by 18 hours, then commence IAP • Temperature ≥ 38 oC
Tenney JH, Where GBS bacteriuria (of any count) is confirmed on urine culture at any stage in pregnancy, a short course of an . Occurrence of pyuria and bacteriuria in asymptomatic hemodialysis patients. Antibiotics for asymptomatic bacteriuria in pregnancy. Levison M,
Antibiotics for treatment of GBS bacteriuria in pregnancy 21,34-36.
Clin Infect Dis. Low DE, Infect Dis Clin North Am. Harding GK, Found inside – Page 146Cystitis □ □ Pyelonephritis □ Renal calculi • Pregnancy-related diagnoses □ Preterm labor □ Preeclampsia ... days Can □ be used to treat GBS bacteriuria □ 500 146 Chapter 3 Care of the Pregnant Woman with Prenatal Conditions.
/ afp Studies of women with diabetes show no difference between initially asymptomatic bacteriuric and nonbacteriuric women in the incidence of UTI, mortality, or progression to diabetic complications at 18 months25 or 14 years.26 In a study of antibiotic therapy versus no therapy for women with diabetes and asymptomatic bacteriuria, antimicrobial therapy did not delay or decrease the frequency of symptomatic UTI or the rate of hospitalization for UTI or other causes at up to three years’ follow-up.27 These studies support the IDSA guidelines2 that screening for or treatment of asymptomatic bacteriuria in women with diabetes is not indicated. Bacteriuria in pregnancy.
Gulmezoglu AM, Nicolle LE,
Bjorkelund C, If you tested positive for GBS and labor has not begun and/or your water has not broken, then you do not need to be treated for GBS during delivery. This bacteria is normally found in the vagina and/or rectum of about 25% of all healthy, adult women. 1987;83:27–33.
Raabe VN, Shane AL. treatment with intravenous antibiotics during labour reduces the risk of transmission of the infection to the baby. Pregnant women who have asymptomatic bacteriuria should be treated with antimicrobial therapy for three to seven days.
Clinically inapparent (asymptomatic) bacteriuria in ambulatory elderly men: epidemiological, clinical, and microbiological findings. 1987;257:1067–71. Biofilms and catheter-associated urinary tract infections.
6. Boscia J, et al. Barriers to Abortion Care and Self-Managed Abortion.
Colicchia LC, Lauderdale DS, Du H, et al.
GBS BACTERIURIA OR GBS URINE INFECTION DURING PREGNANCY . The signs and symptoms of late-onset GBS include: Late-onset GBS could have been passed during delivery, or the baby may have contracted it by coming in contact with someone who has GBS. Intravenous antibiotics (given through IV) are recommended during delivery to reduce the chance of your baby becoming sick. Hoopes JM, Positive maternal GBS culture AT ANY POINT during THIS pregnancy 2. Where GBS bacteriuria (of any count) is confirmed on urine culture at any stage in pregnancy, a short course of an . Combining the leukocyte esterase and nitrite tests results in higher specificity than using either test alone.
For the purposes of the development of the decision analytic model, the pregnant cohort was divided into two universal GBS screening strategies: strategy A, GBS screening at 35 0/7 to 37 6/7 weeks of gestation, with those screening positive treated in the intrapartum period; and strategy B, GBS screening at 36 0/7 to 37 6/7 weeks of gestation, and rescreening for GBS if five weeks had elapsed from the initial screening (and the woman still was pregnant), with those screening positive treated in the intrapartum period.7 Both screening strategies (A and B) were compared to a reference scenario that treated cases of neonatal GBS disease in the absence of maternal GBS screening during pregnancy (no screening). Treatment in the first trimester has been shown to reduce the incidence of symptomatic cystitis and pyelonephritis (25). 36. 1982;146:719–23.
The contributors are internationally recognized for their expertise, making this book invaluable for infectious disease physicians, (internists, pediatricians, and family physicians, microbiologists, epidemiologists, and basic scientists ...
GROUP B STREPTOCOCCUS Because of increasing antimicrobial resistance, it is important not to treat patients with asymptomatic bacteriuria unless there is evidence of potential benefit. Found inside – Page 385C. Patients with bacteriuria are also more likely to have identifiable abnormalities on an intravenous pyelography ... Women with documented GBS bacteriuria in the current pregnancy should be treated at the time of labor or rupture of ... Levison M,
Group B streptococcus (GBS) bacteriuria at any concentration identified at any time in pregnancy represents heavy maternal vaginal–rectal colonization and indicates the need for intrapartum antibiotic prophylaxis Table 1 without the need for a subsequent GBS screening vaginal–rectal culture at 36 0/7–37 6/7 weeks of gestation. Dr. McGlone received his medical degree from the University of Maryland School of Medicine, where he also completed a residency in family medicine. Roberts PL, Villar J,
Prevention of early-onset neonatal group B streptococcal disease: Green-top Guideline No. 1991;114:713–9. The fetus can get GBS during pregnancy. ... confirmed as having GBS bacteriuria in her current pregnancy , further antenatal screening is not required, but IAP is indicated 4,2. 10. Williams M, Zantow E, Turrentine M. Cost effectiveness of latest recommendations for group B streptococci screening in the United States. Prevention of preterm delivery and low birth weight associated with asymptomatic bacteriuria.
Camps MJ, Stamm WE.
a) a previous GBS-infected baby b) GBS bacteriuria of any count during the current pregnancy c) preterm (<37 weeks) labour and imminent birth d) intrapartum fever > 38 0 C e) membrane rupture > 18 hours 2. 20 • 3-day or 7-day treatment Nitrofurantoin 100 mg, 2 times daily; Sulfasoxazole 2 gm initially, then 1 …
For information about the SORT evidence rating system, see page 906 or. None of the remaining planners or authors for this educational activity have relevant financial relationships to disclose with ineligible companies whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. of Family Medicine, University of Maryland School of Medicine, 29 South Paca St., Baltimore, MD 21201 (e-mail: Warren JW,
Warren JW,
EXTENSION OF REVIEW DATE - Queensland Health Diagnosis of bacteriuria in men: specimen collection and culture interpretation.
Harding GK, If you test positive for GBS, this simply means you are a carrier. 2 .
Group B streptococcal (GBS) colonisation, bacteriuria or infection in the current pregnancy.
Routine screening for asymptomatic bacteriuria is recommended in pregnant women, and laboratories should screen urine culture specimens for the presence of GBS in concentrations of 10 4 colony-forming units (cfu)/ml or greater.
Nicolle LE.
Sigurdsson JA. 1982;1:156–8. Anthony WC, GBS bacteriuria during current pregnancy Positive GBS screening culture during current pregnancy (unless a planned cesarean delivery, in the absence of labor or amniotic membrane rupture, is performed) Unknown GBS status (culture not done, incomplete, or results unknown) and any of the following: Manitius A, 1997;157:521–5. Roberts PL,
Contact Found inside – Page 107FOLLOW-UP RECOMMENDATIONS No consensus on screening frequency of ASB in pregnancy, but monthly screening of urine culture after ASB treatment is recommended except GBS (2,3). Patient Monitoring Development of any signs/symptoms of UTI ... Booklet version (PDF) Read and download the GBS in Pregnancy and Newborn Babies Leaflet as a booklet from the Group B Strep Support (GBSS) website.. Harding GK, Oyarzun E, Davis RJ, Results from the prospective population-based study of women in Gothenburg, Sweden.
Found inside – Page 876Group B Streptococcus (GBS) in urine should be treated during the antenatal period. All women who have had GBS bacteriuria during the current pregnancy require GBS prophylaxis intrapartum, as this is indicative of heavy colonisation of ... Miao L, It is unclear if GBS bacteriuria is equivalent to GBS vaginal colonization, but pregnant women with GBS bacteriuria should be treated as GBS carriers and should receive a prophylactic antibiotic during labor.
In June 2019, the American College of Obstetricians and Gynecologists (ACOG) published a new Committee Opinion—Prevention of Group B Streptococcal Early-Onset Disease in Newborns external icon external icon —which all obstetric care providers should now be following.
6th ed. Boscia J,
Group B Streptococcus also known as Group B Strep Infection (GBS) is a type of bacterial infection that can be found in a pregnant woman’s vagina or rectum.
39. Found insideAs the pregnancy advances, upward displacement of the bladder into the abdomen results in elongation of the urethra. ... If the organism responsible for the UTI is Group B Streptococcus (GBS), this will need to be treated with ... et al. 38, No. Prevention of group B streptococcal early-onset disease in newborns: ACOG Committee Opinion, Number 797.
3. Women who are pregnant should be screened for asymptomatic bacteriuria in the first trimester and treated, if positive. Does asymptomatic bacteriuria predict mortality and does antimicrobial treatment reduce mortality in elderly ambulatory women [Published correction appears in Ann Intern Med 1994;121:901]?. Thus, the IDSA does not recommend screening for or treatment of asymptomatic bacteriuria in older patients.2. The test involves a swab of both the vagina and the rectum. Lipsky BA,
Lincoln K,
• Previous pregnancy –one GBS positive and one GBS negative, no infant infections Indications to start treatment for GBS prophylaxis in labour Prelabour risk factors for early-onset GBS disease are: • Previous infant with GBS disease • GBS bacteriuria –any colony count is a risk factor and these women are regarded as colonized at delivery
Asymptomatic bacteriuria in women is associated with a higher preterm delivery rate than women without bacteriuria.
Maynard FM,
Fihn SD,