Utility of deep learning super-resolution in the context of osteoarthritis MRI biomarkers.

Currently, approximately 30% of patients with epilepsy do not have adequate seizure control. A variable-density stack-of-spirals trajectory consists of variable-density spirals in each k(x)-k(y) plane that are located in varying density in the k(z) direction. Measurements between control points were made and compared.Accurate correlation was achieved between MR and histologic images.

Chuapoco, M. R., Choy, M., Schmid, F., Duffy, B. View details for DOI 10.1016/j.neuroimage.2015.03.079, View details for Web of Science ID 000355002900030, View details for DOI 10.1109/LED.2015.2404814, View details for Web of Science ID 000351743900003. A., Choy, M., Kravitz, A. V., Kreitzer, A. C., Lee, J. H. Optogenetic study of networks in epilepsy. Lee, H. J., Weitz, A. J., Bernal-Casas, D., Duffy, B.

Lee, J., Kreitzer, A. C., Singer, A. C., Schiff, N. D. Comparison of fMRI analysis methods for heterogeneous BOLD responses in block design studies.

Lee, J. H., Durand, R., Gradinaru, V., Zhang, F., Goshen, I., Kim, D., Fenno, L. E., Ramakrishnan, C., Deisseroth, K. High-Contrast In Vivo Visualization of Microvessels Using Novel FeCo/GC Magnetic Nanocrystals. In each cohort, optical stimulation was delivered to the right primary motor cortex (M1). Evaluations are carried out within the general linear model (GLM) framework and consist of standard basis sets as well as independent component analysis (ICA). Lee, J. H., Scott, G. C., Pauly, J. M., Nishimura, D. G. Fast 3D imaging using variable-density spiral trajectories with applications to limb perfusion. Lee, J. H., Dumoulin, S. O., Saritas, E. U., Glover, G. H., Wandell, B. Furthermore, these probes distort a significantly smaller volume of voxels compared to tungsten and platinum-iridium electrodes in agarose phantom and in vivo MR images, leading to higher contrast-to-noise ratio in regions proximal to the electrode implantation site during fMRI. This Artist Transformed BTS Members Into Iconic Disney Characters And The Results Are Jaw-Dropping, Park Yu Chun to appear in L’Officiel Hommes Magazine music issue with interview and fashion set. Experimental results show that off-resonance blurring can be successfully corrected to obtain high-resolution images. Comparisons were performed using structural similarity, peak SNR, and RMS error image quality metrics for a multitude of thin-slice downsampling factors. The concentric rings are inherently centric-ordered, provide a smooth weighting in k-space, and enable shorter total scan times. [5], http://www.fk-austria.at/de/n/news/2017/08/austria-holt-nachwuchs-teamspieler-aus-suedkorea/, http://www.fk-austria.at/de/n/news/spielberichte-17-18/08/mit-sieg-in-der-suedstadt-in-die-laenderspielpause-/, http://www.kfa.or.kr/national/player.asp?Query=Grade%3DMU20%26Sumons%3D1439%26Player%3D60785, "Asian Games 2018: Son Heung-min leads Korea Republic to gold", https://en.wikipedia.org/w/index.php?title=Lee_Jin-hyun&oldid=973155081, South Korea under-20 international footballers, South Korea under-23 international footballers, Asian Games gold medalists for South Korea, South Korean expatriate sportspeople in Austria, Articles with Korean-language sources (ko), Creative Commons Attribution-ShareAlike License, * Senior club appearances and goals counted for the domestic league only and correct as of 8 August 2020, This page was last edited on 15 August 2020, at 17:54. In vivo imaging of transplanted stem cells in the central nervous system. Our findings suggest that MDS state-space models can accurately and reliably estimate causal interactions in ofMRI data and further validate their use for estimating causal interactions in fMRI.

View details for Web of Science ID 000266429900031, View details for PubMedCentralID PMC2760085. By combining optogenetic control with fMRI readout, neural activity arising from specific circuit elements defined by genetic identity, cell body location, and axonal projection targets can be monitored in vivo across the whole brain. [2], On August 27, 2017, Lee Jin-hyun made his debut appearance against FC Admira Wacker and he also scored his debut goal at the 76th minute.

With this method, multi slice images with higher in-plane resolutions (0.94 x 0.94 mm(2) for sagittal and 0.62 x 0.62 mm(2) for axial images) are achieved at 1.5 T, without the need for a longer readout. SNR Dependence of Optimal Parameters for Apparent Diffusion Coefficient Measurements. View details for PubMedCentralID PMC4941940. The Lee Lab uses interdisciplinary approaches from biology and engineering to analyze, debug, and manipulate systems-level brain circuits. Nell'onomastica di questa lingua il cognome precede il nome. These result in artifacts with the usually long readout duration of the ss-EPI method.

Previously, FeCo nanocrystals with multilayered graphitic carbon, pyrolytic carbon or inert metals have been obtained, but not in the single-shelled, discrete, chemically functionalized and water-soluble forms desired for biological applications. The results indicate that seizure-like afterdischarges involve several extrahippocampal brain regions that are not recruited by subthreshold optogenetic stimulation of the hippocampus at 20 Hz. Fang, Z., Van Le, N., Choy, M., Lee, J. H. Activation of Direct and Indirect Pathway Medium Spiny Neurons Drives Distinct Brain-wide Responses. To understand the conditions necessary to initiate and terminate seizures, we investigate optogenetically induced hippocampal seizures with LFP, fMRI, and optogenetic inhibition. The spectral information can be used to assess field variation and perform robust fat-water separation. View details for PubMedID 11930050, View details for DOI 10.1148/radiol.2231010420, NIH/NIBIB K99/R00 Award, NIH/NIBIB (2008/2010), NIH Director's New Innovator Award, NIH (2010), Okawa Foundation Research Grant Award, Okawa Foundation (2010), Alfred P. Sloan Foundation Research Fellowship, Alfred P. Sloan Foundation (2012), Epilepsy Therapy Project Award, Epilepsy Foundation (2012), Alzheimer's Association New Investigator Award, Alzheimer's Association (2013), Association of Korean Neuroscientists (AKN) Junior Faculty Research Award, AKN (2013), IEEE EMBS BRAIN Grand Challenge Young Investigator Award, IEEE (2014), NIH/NIA RF1: Study of Alzheimer's Disease, NIH/NIA (2014), NIH/NINDS R01: Study of Traumatic Brain Injury, NIH/NINDS (2014), Stanford Bio-X interdisciplinary seed grant, Stanford Bio-X (2014), NIH/NINDS R01: Study of Basal Ganglia Circuit Dynamics, NIH/NINDS (2015), Beckman Technology Development Grant Award, Beckman Foundation (2016), NIH/NIMH BRAIN R01: Cell-type specific contributions to fMRI signals, NIH/NIMH (2017), Zaffaroni Grant, Zaffaroni Alzheimer’s Disease Translational Research Program (2017), Lina 50+ Award Grand Prize, Lina Foundation (2018), NIH Director's Pioneer Award, NIH/NINDS (2019), BS, Seoul National University, Electrical Engineering, MS, Stanford University, Electrical Engineering, PhD, Stanford University, Electrical Engineering (2004).
Using fMRI in animal models of Alzheimer's disease has the potential to provide us with a more comprehensive understanding of the observations made in human clinical fMRI studies. Liu, J., Lee, H. J., Weitz, A. J., Fang, Z., Lin, P., Choy, M., Fisher, R., Pinskiy, V., Tolpygo, A., Mitra, P., Schiff, N., Lee, J. H. MRI compatible optrodes for simultaneous LFP and optogenetic fMRI investigation of seizure-like afterdischarges. Here, we highlight some of these challenges and discuss potential solutions for researchers interested in performing fMRI in animal models.

A. Thalamic Input to Orbitofrontal Cortex Drives Brain-wide, Frequency-Dependent Inhibition Mediated by GABA and Zona Incerta. We designed and implemented a highly optimised, massively parallel system using graphics processing units (GPUs), which achieves the reconstruction, motion correction, and analysis of 3D volume data in approximately 12.80 ms. As a result, with a 750 ms TR and 4 interleaf fMRI acquisition, we can now conduct sliding window reconstruction, motion correction, analysis and display in approximately 1.7% of the TR. Here, we introduce dynamic causal modeling (DCM) for optogenetic fMRI experiments-which uniquely allow cell-type-specific, brain-wide functional measurements-to parameterize the causal relationships among regions of a distributed brain network with cell type specificity.

The proposed method is robust to physiological noise and enables detection of layer-specific activities in vivo, which cannot be resolved using the highest spatial resolution Nyquist acquisition.The proposed method enables high spatial resolution fMRI that can resolve layer-specific brain activity and demonstrates the significant improvement that CS can bring to high spatial resolution fMRI. Here, by combining FeCo-graphitic carbon shell nanocrystals with high-resolution MRI technique, we demonstrate that such microvessels down to approximately 100 mum can be monitored in high contrast and noninvasively using a conventional 1.5-T clinical MRI system, achieving a diagnostic imaging standard approximating that of the more invasive X-ray angiography. The method has a potential to provide higher signal to noise ratio (SNR) efficiency with reduced imaging artifacts compared to conventional approaches.
The core size of the particles is about 8-10 nm and the overall size is around 20-30 nm. These results demonstrate the potential of a novel neuroimaging-based platform that can be used to identify how a graft's electrical activity influences the brain network in vivo.